This study proposes an intelligent pick-and-pass system and a storage assignment algorithm to improve order-picking operations in e-commerce warehouses. In this paper, the structure of the pick-and-pass system and the idea of the algorithm are presented. The effectiveness of the algorithm is verified by the real data from FineEx, and the order-picking efficiency is improved significantly. This solution can mitigate the pressure brought by labor shortages during E-commerce promotions.