When a complex process is featured with multi-extreme of quality responses as well as high order interactions and constraints among influential factors,parametric response surface method(RSM) fails to fit the real surface and is hard to achieve global optimization;While non-parametric RSM results in poor generalization performance when the sample size is finite and is hard to optimize the response as well.In this paper,the model fitting phase of RSM is described as a sort of restricted small-sam...