When the quan tity of requiremen ts by an activ ity in a supply cha in is too large, a sole depot usua lly can not prov ide a ll the requiremen ts, and it ismuch practica l for in troduc ing multiple depo t s to m eet theneeds. A cco rding to the characterist ics of the m aterial requ irem en t of supp ly chain system s, th is paper p resen t s a m u lt i2depo t supp ly model. By in t roducing the def in it ion of feasib le schem e, w e p resen t a theo rem to determ ine w hether there is a feasib le schem e, and the co rresponding m ethod to ob tain a feasib le schem e. How ever a feasib le schem e m ay include so m any depo t s that som et im es it is unp ract ical. F rom the po in t view of reliab ility and co st, a schem e w ith few er depo t s is p referred. A s fo r examp le, in an inven to ry system , the num ber of invo lved depo t sm ay direct ly affect the to tal set up co st. Therefo re, as far as the reliab ility and co st are concerned, th is paper p resen t s a co rresponding heu rist ic m ethod. F inally, in tegrat ing the model in sof tw are system s is b rief ly discu ssed