The relationship between negative affect and creativity is ambiguous in previous literature. From the perspective of the contingency, the study examined the relationship between negative affects and creativity by considering organizational identification and professional identification. The study investigated 472 employees of high-tech enterprises. The results showed that: 1) Negative affect were negatively related to employee creativity; 2) Both organizational identification and professional identification enhanced the negative effect of negative affect on employee creativity. In the negative affect, the employee with highly organization identification or professional identification was less inclined to innovate. 3) Interaction between organizational identification and professional identification played moderate role in the relationship between negative affect and creativity.Under the “double high” ( high organizational identity of higher professional identity) conditions, negative affect has a significant negative impact on employee creativity; under the two “one high and one low”conditions, the relationship between negative affect and creativity is not significant; while under the “double low”conditions, the negative affect positively impacts the employee creativity and its impact is significant. The results indicated it was reasonable to study negative affect-creativity relationship from the perspective of organizational identification and professional identification. They can improve the performance of the model, and can help to clarify the relationship between negative affect and creativity. The study provided theoretical support for enterprise innovation management practice.