Exploring the time-lag effect of environmental regulation policies on industrial structure change is the key to understand the impact of policies on industrial structure change in the time dimension. Beijing-Tianjin-Hebei and surrounding regions are selected as the research object. Through quantitative analysis of the environmental regulation policies at the central level and those of Beijing-Tianjin-Hebei and surrounding regions from 2004 to 2016，the time-lag effect of“central + local”multiple environmental regulation policies on industrial structure change is studied. The results show that: 1) The time-lag effect of environmental regulation policies on industrial structure change is multi-period，and the effect of environmental regulation policies is different in different periods. Industrial structure change is also the result of the effect of multi-period environmental regulation policies，and the impact of multi-period environmental regulation policies on industrial structure change is inverted U-shaped. 2) Environmental regulation policies usually have immediate regulatory effect on polluting enterprises in the year of promulgation，but the impact is strong and short-lived，which will cause polluting enterprises to make temporary response in the short term. 3) From the third year，the environmental regulation policies have played a continuous and stable role in regulating industrial structure change， making the secondary industrial structure in Beijing-Tianjin-Hebei and surrounding regions change in the direction of target expected by the policies.