This paper focuses on the key frontier research achievements of the Management Science and Engineering discipline in China from 2021 to 2025. Based on 9 864 papers published in 46 international frontier journals, and including 197 related papers from 7 world-leading comprehensive journals, this study systematically examines the current research progress and hot trends in the Management Science and Engineering discipline in China by using bibliometric and text mining methods. The research results show that: First, the research level and scientific research competitiveness of the Management Science and Engineering discipline in China have steadily improved, and the research results are closely related to the local context; Second, The National Natural Science Foundation of China has become the core funding agency for the research results of the Management Science and Engineering discipline in China; Third, the research hotspots in the Management Science and Engineering discipline in China focus on system risks, and the methodology shows a trend of integration with artificial intelligence.